Rhodopsin (opsd_bovin)

FAMILY

Class A (Rhodopsin) Sensory receptors Opsins Rhodopsin

GENE

RHO

ORGANISM

Bovine (Bos taurus)

ALT. NAMES

Rhodopsin

SOURCE

SWISSPROT

SEQUENCE

N-term        
M
N
G
T
E
G
P
N
F
Y
10
                   
V
P
F
S
N
K
T
G
V
V
20
                   
R
S
P
F
E
A
P
Q
Y
Y
30
    TM1          
L
A
E
P
W
Q
F
S
M
L
40
                   
A
A
Y
M
F
L
L
I
M
L
50
                   
G
F
P
I
N
F
L
T
L
Y
60
          ICL1  
V
T
V
Q
H
K
K
L
R
T
70
TM2              
P
L
N
Y
I
L
L
N
L
A
80
                   
V
A
D
L
F
M
V
F
G
G
90
                   
F
T
T
T
L
Y
T
S
L
H
100
  ECL1 TM3    
G
Y
F
V
F
G
P
T
G
C
110
                   
N
L
E
G
F
F
A
T
L
G
120
                   
G
E
I
A
L
W
S
L
V
V
130
                   
L
A
I
E
R
Y
V
V
V
C
140
  ICL2          
K
P
M
S
N
F
R
F
G
E
150
TM4              
N
H
A
I
M
G
V
A
F
T
160
                   
W
V
M
A
L
A
C
A
A
P
170
        ECL2    
P
L
V
G
W
S
R
Y
I
P
180
                   
E
G
M
Q
C
S
C
G
I
D
190
                   
Y
Y
T
P
H
E
E
T
N
N
200
TM5              
E
S
F
V
I
Y
M
F
V
V
210
                   
H
F
I
I
P
L
I
V
I
F
220
                   
F
C
Y
G
Q
L
V
F
T
V
230
                   
K
E
A
A
A
Q
Q
Q
E
S
240
TM6              
A
T
T
Q
K
A
E
K
E
V
250
                   
T
R
M
V
I
I
M
V
I
A
260
                   
F
L
I
C
W
L
P
Y
A
G
270
                   
V
A
F
Y
I
F
T
H
Q
G
280
ECL3 TM7      
S
D
F
G
P
I
F
M
T
I
290
                   
P
A
F
F
A
K
T
S
A
V
300
                   
Y
N
P
V
I
Y
I
M
M
N
310
H8                
K
Q
F
R
N
C
M
V
T
T
320
    C-term    
L
C
C
G
K
N
P
L
G
D
330
                   
D
E
A
S
T
T
V
S
K
T
340
               
E
T
S
Q
V
A
P
A

LINKS

DIAGRAMS

ICL1 K K L R ICL1ECL1 Y F V F ECL1ICL2 P M S N F R F ICL2ECL2 W S R Y I P E G M Q C S C G I D Y Y T P H E E T ECL2ICL3 Q E ICL3ECL3 Q G S D F ECL3N-term M N G T E G P N F Y V P F S N K T G V V R S P F E A P Q Y Y L A N-termC-term C G K N P L G D D E A S T T V S K T E T S Q V A P A C-term E P W Q F S M L A A Y M F L L I M L G F P I N F L T L Y V T V Q H T P L N Y I L L N L A V A D L F M V F G G F T T T L Y T S L H G G P T G C N L E G F F A T L G G E I A L W S L V V L A I E R Y V V V C K G E N H A I M G V A F T W V M A L A C A A P P L V G N N E S F V I Y M F V V H F I I P L I V I F F C Y G Q L V F T V K E A A A Q Q S A T T Q K A E K E V T R M V I I M V I A F L I C W L P Y A G V A F Y I F T H G P I F M T I P A F F A K T S A V Y N P V I Y I M M N K Q M V T F R N C T L C
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Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A

F N I P F G L M I L L F M Y A A L M S F 1 L N L A V A D L F M V G F G F T T T L Y T 2 V V L S W L A I E G G L T A F F G E L N 3 A I M G V A F T W V M A L A C A A P P L 4 Y C F F I V I L P I I F H V V F M Y I V F 5 I I M V I A F L I C W L P Y A G V A F Y 6 V P N Y V A S T K A F F A P I T M F I 7
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Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A

MUTATIONS

PHYSIOLOGICAL LIGANDS

No physiological ligands available

STRUCTURE MODELS

No structure models have been generated as experimental structures are available (see below).

STRUCTURES

Found 60 structure(s) - view all details on the Structures page

PDBs: 1F88, 1HZX, 1L9H, 1GZM, 1U19, 2HPY, 2G87, 2I35, 2I36, 2I37, 2J4Y, 2PED, 3CAP, 3C9L, 3C9M, 3DQB, 3OAX, 3PQR, 3PXO, 2X72, 4A4M, 4BEZ, 4BEY, 4J4Q, 4PXF, 4X1H, 5DYS, 5EN0, 5TE3, 5TE5, 5WKT, 6FK6, 6FK7, 6FK8, 6FK9, 6FKA, 6FKB, 6FKC, 6FKD, 6FUF, 6QNO, 6OY9, 6OYA, 6OFJ, 6NWE, 6PEL, 6PGS, 6PH7, 7MT8, 7MT9, 7MTA, 7MTB, 7ZBC, 7ZBE, 8A6C, 8A6D, 8A6E, 8FCZ, 8FD0, 8FD1