TAS2R39 (t2r39_human)
FAMILY
Class T2 (Taste 2) Sensory receptors Taste 2 receptors TAS2R39
GENE
TAS2R39
ORGANISM
Human (Homo sapiens)
ALT. NAMES
Taste receptor type 2 member 39, T2R39, Taste receptor type 2 member 57, T2R57
SOURCE
SWISSPROT
SEQUENCE
N-term | |||||||||
M
|
L
|
G
|
R
|
C
|
F
|
P
|
P
|
D
|
T
|
10 |
K
|
E
|
K
|
Q
|
Q
|
L
|
R
|
M
|
T
|
K
|
20 |
L
|
C
|
D
|
P
|
A
|
E
|
S
|
E
|
L
|
S
|
30 |
TM1 | |||||||||
P
|
F
|
L
|
I
|
T
|
L
|
I
|
L
|
A
|
V
|
40 |
L
|
L
|
A
|
E
|
Y
|
L
|
I
|
G
|
I
|
I
|
50 |
A
|
N
|
G
|
F
|
I
|
M
|
A
|
I
|
H
|
A
|
60 |
A
|
E
|
W
|
V
|
Q
|
N
|
K
|
A
|
V
|
S
|
70 |
TM2 | |||||||||
T
|
S
|
G
|
R
|
I
|
L
|
V
|
F
|
L
|
S
|
80 |
V
|
S
|
R
|
I
|
A
|
L
|
Q
|
S
|
L
|
M
|
90 |
M
|
L
|
E
|
I
|
T
|
I
|
S
|
S
|
T
|
S
|
100 |
ECL1 | TM3 | ||||||||
L
|
S
|
F
|
Y
|
S
|
E
|
D
|
A
|
V
|
Y
|
110 |
Y
|
A
|
F
|
K
|
I
|
S
|
F
|
I
|
F
|
L
|
120 |
N
|
F
|
C
|
S
|
L
|
W
|
F
|
A
|
A
|
W
|
130 |
L
|
S
|
F
|
F
|
Y
|
F
|
V
|
K
|
I
|
A
|
140 |
ICL2 | |||||||||
N
|
F
|
S
|
Y
|
P
|
L
|
F
|
L
|
K
|
L
|
150 |
TM4 | |||||||||
R
|
W
|
R
|
I
|
T
|
G
|
L
|
I
|
P
|
W
|
160 |
L
|
L
|
W
|
L
|
S
|
V
|
F
|
I
|
S
|
F
|
170 |
S
|
H
|
S
|
M
|
F
|
C
|
I
|
N
|
I
|
C
|
180 |
ECL2 | |||||||||
T
|
V
|
Y
|
C
|
N
|
N
|
S
|
F
|
P
|
I
|
190 |
H
|
S
|
S
|
N
|
S
|
T
|
K
|
K
|
T
|
Y
|
200 |
L
|
S
|
E
|
I
|
N
|
V
|
V
|
G
|
L
|
A
|
210 |
TM5 | |||||||||
F
|
F
|
F
|
N
|
L
|
G
|
I
|
V
|
T
|
P
|
220 |
L
|
I
|
M
|
F
|
I
|
L
|
T
|
A
|
T
|
L
|
230 |
L
|
I
|
L
|
S
|
L
|
K
|
R
|
H
|
T
|
L
|
240 |
ICL3 | |||||||||
H
|
M
|
G
|
S
|
N
|
A
|
T
|
G
|
S
|
N
|
250 |
TM6 | |||||||||
D
|
P
|
S
|
M
|
E
|
A
|
H
|
M
|
G
|
A
|
260 |
I
|
K
|
A
|
I
|
S
|
Y
|
F
|
L
|
I
|
L
|
270 |
Y
|
I
|
F
|
N
|
A
|
V
|
A
|
L
|
F
|
I
|
280 |
Y
|
L
|
S
|
N
|
M
|
F
|
D
|
I
|
N
|
S
|
290 |
TM7 | |||||||||
L
|
W
|
N
|
N
|
L
|
C
|
Q
|
I
|
I
|
M
|
300 |
A
|
A
|
Y
|
P
|
A
|
S
|
H
|
S
|
I
|
L
|
310 |
H8 | |||||||||
L
|
I
|
Q
|
D
|
N
|
P
|
G
|
L
|
R
|
R
|
320 |
A
|
W
|
K
|
R
|
L
|
Q
|
L
|
R
|
L
|
H
|
330 |
C-term | ||||||||
L
|
Y
|
P
|
K
|
E
|
W
|
T
|
L
|
|
DIAGRAMS
Pick color:
Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A
Pick color:
Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A
MUTATIONS
PHYSIOLOGICAL LIGANDS
No physiological ligands available
STRUCTURE MODELS
STRUCTURES
No structures available