TAS2R60 (t2r60_human)
FAMILY
Class T2 (Taste 2) Sensory receptors Taste 2 receptors TAS2R60
GENE
TAS2R60
ORGANISM
Human (Homo sapiens)
ALT. NAMES
Taste receptor type 2 member 60, T2R60, Taste receptor type 2 member 56, T2R56
SOURCE
SWISSPROT
SEQUENCE
N-term | |||||||||
M
|
N
|
G
|
D
|
H
|
M
|
V
|
L
|
G
|
S
|
10 |
TM1 | |||||||||
S
|
V
|
T
|
D
|
K
|
K
|
A
|
I
|
I
|
L
|
20 |
V
|
T
|
I
|
L
|
L
|
L
|
L
|
R
|
L
|
V
|
30 |
A
|
I
|
A
|
G
|
N
|
G
|
F
|
I
|
T
|
A
|
40 |
A
|
L
|
G
|
V
|
E
|
W
|
V
|
L
|
R
|
R
|
50 |
ICL1 | TM2 | ||||||||
M
|
L
|
L
|
P
|
C
|
D
|
K
|
L
|
L
|
V
|
60 |
S
|
L
|
G
|
A
|
S
|
R
|
F
|
C
|
L
|
Q
|
70 |
S
|
V
|
V
|
M
|
G
|
K
|
T
|
I
|
Y
|
V
|
80 |
ECL1 | TM3 | ||||||||
F
|
L
|
H
|
P
|
M
|
A
|
F
|
P
|
Y
|
N
|
90 |
P
|
V
|
L
|
Q
|
F
|
L
|
A
|
F
|
Q
|
W
|
100 |
D
|
F
|
L
|
N
|
A
|
A
|
T
|
L
|
W
|
S
|
110 |
S
|
T
|
W
|
L
|
S
|
V
|
F
|
Y
|
C
|
V
|
120 |
ICL2 | |||||||||
K
|
I
|
A
|
T
|
F
|
T
|
H
|
P
|
V
|
F
|
130 |
TM4 | |||||||||
F
|
W
|
L
|
K
|
H
|
K
|
L
|
S
|
G
|
W
|
140 |
L
|
P
|
W
|
M
|
L
|
F
|
S
|
S
|
V
|
G
|
150 |
L
|
S
|
S
|
F
|
T
|
T
|
I
|
L
|
F
|
F
|
160 |
ECL2 | |||||||||
I
|
G
|
N
|
H
|
R
|
M
|
Y
|
Q
|
N
|
Y
|
170 |
L
|
R
|
N
|
H
|
L
|
Q
|
P
|
W
|
N
|
V
|
180 |
T
|
G
|
D
|
S
|
I
|
R
|
S
|
Y
|
C
|
E
|
190 |
TM5 | |||||||||
K
|
F
|
Y
|
L
|
F
|
P
|
L
|
K
|
M
|
I
|
200 |
T
|
W
|
T
|
M
|
P
|
T
|
A
|
V
|
F
|
F
|
210 |
I
|
C
|
M
|
I
|
L
|
L
|
I
|
T
|
S
|
L
|
220 |
G
|
R
|
H
|
R
|
K
|
K
|
A
|
L
|
L
|
T
|
230 |
ICL3 | TM6 | ||||||||
T
|
S
|
G
|
F
|
R
|
E
|
P
|
S
|
V
|
Q
|
240 |
A
|
H
|
I
|
K
|
A
|
L
|
L
|
A
|
L
|
L
|
250 |
S
|
F
|
A
|
M
|
L
|
F
|
I
|
S
|
Y
|
F
|
260 |
L
|
S
|
L
|
V
|
F
|
S
|
A
|
A
|
G
|
I
|
270 |
ECL3 | TM7 | ||||||||
F
|
P
|
P
|
L
|
D
|
F
|
K
|
F
|
W
|
V
|
280 |
W
|
E
|
S
|
V
|
I
|
Y
|
L
|
C
|
A
|
A
|
290 |
V
|
H
|
P
|
I
|
I
|
L
|
L
|
F
|
S
|
N
|
300 |
H8 | |||||||||
C
|
R
|
L
|
R
|
A
|
V
|
L
|
K
|
S
|
R
|
310 |
R
|
S
|
S
|
R
|
C
|
G
|
T
|
P
|
DIAGRAMS
Pick color:
Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A
Pick color:
Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A
MUTATIONS
PHYSIOLOGICAL LIGANDS
No physiological ligands available
STRUCTURE MODELS
STRUCTURES
No structures available