CRF1 receptor

GPCR CLASS (FAMILY)

Class B1 (Secretin)

PDB CODE

8GTI

SPECIES

Homo sapiens

RESOLUTION

2.2 Å

PREFERRED CHAIN

A

REFERENCE

10.1038/S12276-023-01082-1

PUBLICATION DATE

Sept. 13, 2023

3D VIEW

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LIGAND INTERACTIONS

56 interactions (Click to see)

LIGANDS

8-(4-bromo-2,6-dimethoxyphenyl)-N-butyl-N-(cyclopropylmethyl)-2,7-dimethylpyrazolo[1,5-a][1,3,5]triazin-4-amine - Antagonist pubchem

PHYSIOLOGICAL LIGANDS

urocortin 1, urocortin 2, corticotrophin-releasing hormone