Structure information

κ receptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

6B73

SPECIES

Homo sapiens

RESOLUTION

3.100

PREFERRED CHAIN

A

REFERENCE

10.1016/J.CELL.2017.12.011

PUBLICATION DATE

Jan. 17, 2018

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
MP1104 L135 3.29x29 TM3 hydrophobic
MP1104 D138 3.32x32 TM3 polar (charge-assisted hydrogen bond)
MP1104 Y139 3.33x33 TM3 polar (hydrogen bond)
MP1104 Y139 3.33x33 TM3 Van der Waals
MP1104 M142 3.36x36 TM3 Van der Waals
MP1104 M142 3.36x36 TM3 hydrophobic
MP1104 C210 45.50x50 ECL2 hydrophobic
MP1104 C210 45.50x50 ECL2 Van der Waals
MP1104 V230 5.42x43 TM5 Van der Waals
MP1104 W287 6.48x48 TM6 Van der Waals
MP1104 W287 6.48x48 TM6 hydrophobic
MP1104 I294 6.55x55 TM6 Van der Waals
MP1104 I294 6.55x55 TM6 hydrophobic
MP1104 Y312 7.35x34 TM7 Van der Waals
MP1104 I316 7.39x38 TM7 Van der Waals
MP1104 G319 7.42x41 TM7 Van der Waals
MP1104 Y320 7.43x42 TM7 Van der Waals
MP1104 Y320 7.43x42 TM7 hydrophobic

Ligands

MP1104

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Residue Diagrams

S N G V L G V V F V V S Y V A T I I V P 1 F N L A L A D A L V T T T M P F Q S T V 2 M T L T F I S T F M N Y Y D I S I V I K 3 A K I I N I C I W L L S S S V G I S A I 4 Y C V I I I L V P I V F A F I F V C I K M 5 L V V V A V F V V C W T P I H I F I L V 6 I P N L S S N T Y G L A I C F Y Y S S 7
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ICL1 T K M K ICL1ECL1 S W P F ECL1ICL2 P V K A L D F R ICL2ECL2 G T K V R E D V D V I E C S L Q F P D D ECL2ICL3 R L L S G ICL3ECL3 S T S H ECL3N-term M D S P I Q I F R G E P G P T C A P S A C L P P N S S A W F P G W A E P D S N G S A G S E D A Q L E P A H I S P N-termC-term P L K M R M E R Q S T S R V R N T V Q D P A Y L R D I D G M N K P V C-term A I P V I I T A V Y S V V F V V G L V G N S L V M F V I I R Y T A T N I Y I F N L A L A D A L V T T T M P F Q S T V Y L M N G D V L C K I V I S I D Y Y N M F T S I F T L T M M S V D R Y I A V C H T P L K A K I I N I C I W L L S S S V G I S A I V L G D Y S W W D L F M K I C V F I F A F V I P V L I I I V C Y T L M I L R L K S V S R E K D R N L R R I T R L V L V V V A V F V V C W T P I H I F I L V E A L G S T A A L S S Y Y F C I A L G Y T N S S L N P I L Y A F L D E N F R D F K R C F C F
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Residue Table


GPCRdb(A)
GPCRdb(A)
κ receptor
TM3
3x29 3.29x29 I135
3x32 3.32x32 D138
3x33 3.33x33 Y139
3x36 3.36x36 M142
ECL2
45x50 45.50x50 C210
TM5
5x43 5.42x43 V230
TM6
6x48 6.48x48 W287
6x55 6.55x55 I294
TM7
7x34 7.35x34 Y312
7x38 7.39x38 I316
7x41 7.42x41 G319
7x42 7.43x42 Y320