GPCRdb

bradykinin

Agent/drug
Bioactivity

bradykinin

SMILES	None
InChIKey	QXZGBUJJYSLZLT-FDISYFBBSA-N
Sequence	RPPGFSPFR

Chemical Properties

Hydrogen bond acceptors	None
Hydrogen bond donors	None
Rotatable bonds	None
Molecular weight (Da)

Database connections

Guide To Pharmacology DrugBank ChEMBL_compound_ids PubChem GPCRdb
Structure pdb	7F2O 7F6H

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

B₁	BKRB1	Human	Bradykinin	A	pKi	4.00	4.00	4.00	Guide to Pharmacology
B₁	BKRB1	Mouse	Bradykinin	A	pKi	6.70	6.70	6.70	Guide to Pharmacology
B₁	BKRB1	Rat	Bradykinin	A	pKi	5.10	5.20	5.30	Guide to Pharmacology
B₂	BKRB2	Mouse	Bradykinin	A	pKd	9.40	9.40	9.40	Guide to Pharmacology
B₂	BKRB2	Human	Bradykinin	A	pKi	8.96	9.49	10.19	ChEMBL
B₂	BKRB2	Rat	Bradykinin	A	pKi	9.34	9.34	9.34	ChEMBL

Showing 1 to 6 of 6 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

B₂	BKRB2	Mouse	Bradykinin	A	pIC50	9.30	9.30	9.30	Guide to Pharmacology
B₂	BKRB2	Human	Bradykinin	A	pIC50	8.74	8.74	8.74	ChEMBL
B₂	BKRB2	Human	Bradykinin	A	pEC50	10.31	10.31	10.31	ChEMBL
B₂	BKRB2	Human	Bradykinin	A	pIC50	7.00	8.15	9.30	Guide to Pharmacology
OR51E2	O51E2	Human	Odorant family 51	O1	pEC50	8.89	8.89	8.89	ChEMBL

Showing 1 to 5 of 5 entries

bradykinin

Drug properties

Molecular type	Peptide
Physiological/Surrogate	Endogenous
Approved drug	Yes

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV 0

Database connections

Guide To Pharmacology DrugBank ChEMBL_compound_ids PubChem GPCRdb
Structure pdb	7F2O 7F6H

Compound is not listed as a drug.