Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A
|
GPCRdb(A)
|
OR51E2
Human |
|
|---|---|---|
| TM1 | ||
| 1x31 | A22 | |
| 1x32 | H23 | |
| 1x33 | F24 | |
| 1x34 | W25 | |
| 1x35 | V26 | |
| 1x36 | G27 | |
| 1x37 | F28 | |
| 1x38 | P29 | |
| 1x39 | L30 | |
| 1x40 | L31 | |
| 1x41 | S32 | |
| 1x42 | M33 | |
| 1x43 | Y34 | |
| 1x44 | V35 | |
| 1x45 | V36 | |
| 1x46 | A37 | |
| 1x47 | M38 | |
| 1x48 | F39 | |
| 1x49 | G40 | |
| 1x50 | N41 | |
| 1x51 | C42 | |
| 1x52 | I43 | |
| 1x53 | V44 | |
| 1x54 | V45 | |
| 1x55 | F46 | |
| 1x56 | I47 | |
| 1x57 | V48 | |
| 1x58 | R49 | |
| 1x59 | T50 | |
| 1x60 | E51 | |
| ICL1 | ||
| 12x48 | R52 | |
| 12x49 | S53 | |
| 12x50 | L54 | |
| 12x51 | H55 | |
| TM2 | ||
| 2x37 | A56 | |
| 2x38 | P57 | |
| 2x39 | M58 | |
| 2x40 | Y59 | |
| 2x41 | L60 | |
| 2x42 | F61 | |
| 2x43 | L62 | |
| 2x44 | C63 | |
| 2x45 | M64 | |
| 2x46 | L65 | |
| 2x47 | A66 | |
| 2x48 | A67 | |
| 2x49 | I68 | |
| 2x50 | D69 | |
| 2x51 | L70 | |
| 2x52 | A71 | |
| 2x53 | L72 | |
| 2x54 | S73 | |
| 2x55 | T74 | |
| 2x56 | S75 | |
| 2x57 | T76 | |
| 2x58 | M77 | |
| 2x59 | P78 | |
| 2x60 | K79 | |
| 2x61 | I80 | |
| 2x62 | L81 | |
| 2x63 | A82 | |
| 2x64 | L83 | |
| 2x65 | F84 | |
| 2x66 | W85 | |
| 2x67 | F86 | |
| 2x68 | D87 | |
| TM3 | ||
| 3x21 | S92 | |
| 3x22 | F93 | |
| 3x23 | E94 | |
| 3x24 | A95 | |
| 3x25 | C96 | |
| 3x26 | L97 | |
| 3x27 | T98 | |
| 3x28 | Q99 | |
| 3x29 | M100 | |
| 3x30 | F101 | |
| 3x31 | F102 | |
| 3x32 | I103 | |
| 3x33 | H104 | |
| 3x34 | A105 | |
| 3x35 | L106 | |
| 3x36 | S107 | |
| 3x37 | A108 | |
| 3x38 | I109 | |
| 3x39 | E110 | |
| 3x40 | S111 | |
| 3x41 | T112 | |
| 3x42 | I113 | |
| 3x43 | L114 | |
| 3x44 | L115 | |
| 3x45 | A116 | |
| 3x46 | M117 | |
| 3x47 | A118 | |
| 3x48 | F119 | |
| 3x49 | D120 | |
| 3x50 | R121 | |
| 3x51 | Y122 | |
| 3x52 | V123 | |
| 3x53 | A124 | |
| 3x54 | I125 | |
| 3x55 | C126 | |
| 3x56 | H127 | |
| ICL2 | ||
| 34x50 | P128 | |
| 34x51 | L129 | |
| 34x52 | R130 | |
| 34x53 | H131 | |
| 34x54 | A132 | |
| 34x55 | A133 | |
| 34x56 | V134 | |
| 34x57 | L135 | |
| TM4 | ||
| 4x38 | N136 | |
| 4x39 | N137 | |
| 4x40 | T138 | |
| 4x41 | V139 | |
| 4x42 | T140 | |
| 4x43 | A141 | |
| 4x44 | Q142 | |
| 4x45 | I143 | |
| 4x46 | G144 | |
| 4x47 | I145 | |
| 4x48 | V146 | |
| 4x49 | A147 | |
| 4x50 | V148 | |
| 4x51 | V149 | |
| 4x52 | R150 | |
| 4x53 | G151 | |
| 4x54 | S152 | |
| 4x55 | L153 | |
| 4x56 | F154 | |
| 4x57 | F155 | |
| 4x58 | F156 | |
| 4x59 | P157 | |
| 4x60 | L158 | |
| 4x61 | P159 | |
| 4x62 | L160 | |
| 4x63 | L161 | |
| 4x64 | I162 | |
| 4x65 | K163 | |
| 4x66 | R164 | |
| 4x67 | L165 | |
| ECL2 | ||
| 45x50 | C178 | |
| 45x51 | V179 | |
| 45x52 | H180 | |
| TM5 | ||
| 5x33 | T191 | |
| 5x34 | L192 | |
| 5x35 | P193 | |
| 5x36 | N194 | |
| 5x37 | V195 | |
| 5x38 | V196 | |
| 5x39 | Y197 | |
| 5x40 | G198 | |
| 5x41 | L199 | |
| 5x42 | T200 | |
| 5x43 | A201 | |
| 5x44 | I202 | |
| 5x45 | L203 | |
| 5x46 | L204 | |
| 5x461 | V205 | |
| 5x47 | M206 | |
| 5x48 | G207 | |
| 5x49 | V208 | |
| 5x50 | D209 | |
| 5x51 | V210 | |
| 5x52 | M211 | |
| 5x53 | F212 | |
| 5x54 | I213 | |
| 5x55 | S214 | |
| 5x56 | L215 | |
| 5x57 | S216 | |
| 5x58 | Y217 | |
| 5x59 | F218 | |
| 5x60 | L219 | |
| 5x61 | I220 | |
| 5x62 | I221 | |
| 5x63 | R222 | |
| 5x64 | T223 | |
| 5x65 | V224 | |
| 5x66 | L225 | |
| 5x67 | Q226 | |
| 5x68 | L227 | |
| TM6 | ||
| 6x26 | S229 | |
| 6x27 | K230 | |
| 6x28 | S231 | |
| 6x29 | E232 | |
| 6x30 | R233 | |
| 6x31 | A234 | |
| 6x32 | K235 | |
| 6x33 | A236 | |
| 6x34 | F237 | |
| 6x35 | G238 | |
| 6x36 | T239 | |
| 6x37 | C240 | |
| 6x38 | V241 | |
| 6x39 | S242 | |
| 6x40 | H243 | |
| 6x41 | I244 | |
| 6x42 | G245 | |
| 6x43 | V246 | |
| 6x44 | V247 | |
| 6x45 | L248 | |
| 6x46 | A249 | |
| 6x47 | F250 | |
| 6x48 | Y251 | |
| 6x49 | V252 | |
| 6x50 | P253 | |
| 6x51 | L254 | |
| 6x52 | I255 | |
| 6x53 | G256 | |
| 6x54 | L257 | |
| 6x55 | S258 | |
| 6x56 | V259 | |
| 6x57 | V260 | |
| 6x58 | H261 | |
| 6x59 | R262 | |
| 6x60 | F263 | |
| 6x61 | G264 | |
| TM7 | ||
| 7x29 | H268 | |
| 7x30 | P269 | |
| 7x31 | I270 | |
| 7x32 | V271 | |
| 7x33 | R272 | |
| 7x34 | V273 | |
| 7x35 | V274 | |
| 7x36 | M275 | |
| 7x37 | G276 | |
| 7x38 | D277 | |
| 7x39 | I278 | |
| 7x40 | Y279 | |
| 7x41 | L280 | |
| 7x42 | L281 | |
| 7x43 | L282 | |
| 7x45 | P283 | |
| 7x46 | P284 | |
| 7x47 | V285 | |
| 7x48 | I286 | |
| 7x49 | N287 | |
| 7x50 | P288 | |
| 7x51 | I289 | |
| 7x52 | I290 | |
| 7x53 | Y291 | |
| 7x54 | G292 | |
| 7x55 | A293 | |
| 7x56 | K294 | |
| H8 | ||
| 8x47 | T295 | |
| 8x48 | K296 | |
| 8x49 | Q297 | |
| 8x50 | I298 | |
| 8x51 | R299 | |
| 8x52 | T300 | |
| 8x53 | R301 | |
| 8x54 | V302 | |
| 8x55 | L303 | |
| 8x56 | A304 | |
| 8x57 | M305 | |
| 8x58 | F306 | |
| 8x59 | K307 | |
| 8x60 | I308 | |