Structure information

BLT1 receptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

5X33

SPECIES

Cavia porcellus

RESOLUTION

3.700

PREFERRED CHAIN

A

REFERENCE

10.1038/NCHEMBIO.2547

PUBLICATION DATE

Jan. 3, 2018

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
BIIL 260 D66 2.50x50 TM2 polar (charge-assisted hydrogen bond)
BIIL 260 V69 2.53x53 TM2 Van der Waals
BIIL 260 V69 2.53x53 TM2 hydrophobic
BIIL 260 F76 2.60x60 TM2 hydrophobic
BIIL 260 F76 2.60x60 TM2 Van der Waals
BIIL 260 F79 2.63x63 TM2 hydrophobic
BIIL 260 L80 2.64x64 TM2 hydrophobic
BIIL 260 L80 2.64x64 TM2 Van der Waals
BIIL 260 H96 3.29x29 TM3 polar (hydrogen bond)
BIIL 260 H96 3.29x29 TM3 Van der Waals
BIIL 260 C99 3.32x32 TM3 hydrophobic
BIIL 260 C99 3.32x32 TM3 Van der Waals
BIIL 260 S102 3.35x35 TM3 Van der Waals
BIIL 260 M103 3.36x36 TM3 Van der Waals
BIIL 260 M103 3.36x36 TM3 hydrophobic
BIIL 260 S106 3.39x39 TM3 polar (hydrogen bond)
BIIL 260 W236 6.48x48 TM6 Van der Waals
BIIL 260 W236 6.48x48 TM6 aromatic (edge-to-face)
BIIL 260 K267 7.36x35 TM7 Van der Waals
BIIL 260 I270 7.39x38 TM7 hydrophobic
BIIL 260 I270 7.39x38 TM7 Van der Waals
BIIL 260 A273 7.42x41 TM7 Van der Waals
BIIL 260 F274 7.43x42 TM7 hydrophobic
BIIL 260 F274 7.43x42 TM7 Van der Waals
BIIL 260 S276 7.45x45 TM7 polar (hydrogen bond)
BIIL 260 S277 7.46x46 TM7 Van der Waals

Ligands

BIIL 260

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Residue Diagrams

T N G P L G V V M S V S L L I M A L L P 1 L N L A L A D L A V L L T A P F F L H F 2 A T I L L V S A Y M S V G C I Y H C L R 3 A R W L L V G I W G A S F L L A T P V 4 Y S A V V I L F P V V F G T F A E F L L H 5 V I I I L A F A A F W L P Y H V V D L V 6 L P N V S S S L F A L A I C V K R A N 7
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ICL1 M R K R ICL1ECL1 T W S F ECL1ICL2 P F L S Q K V R ICL2ECL2 K V V K L T N E T D L C L A V Y P ECL2ICL3 R F H R ICL3ECL3 G T L D Q ECL3N-term M D R N T T T R A A S P S G S N N-termC-term G V G F V A K L L E A T G S E A F S T R R G G T L A Q T V K G I P M A P E P G A S G S L D G L K Q S E S D C-term T F I P L L A M I L L S V S M V V G L P G N T F V V W S I L K R S V T A L M V L N L A L A D L A V L L T A P F F L H F L T W H K L A G C R L C H Y I C G V S M Y A S V L L I T A M S L D R S L A V A S T K T A A R W L L V G I W G A S F L L A T P V L A F R S D R H K A F H L L F E A F T G F V V P F L I V V A S Y A D I S R R L R V R R R R T G R L V V I I I L A F A A F W L P Y H V V D L V E G S R V L A S K Q Q L R N A R K V C I A L A F L S S S V N P L L Y A C A G G G L L R S A
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Residue Table


GPCRdb(A)
GPCRdb(A)
BLT1 receptor
TM2
2x50 2.50x50 D66
2x53 2.53x53 V69
2x60 2.60x60 F76
2x63 2.63x63 F79
2x64 2.64x64 L80
TM3
3x29 3.29x29 H96
3x32 3.32x32 C99
3x35 3.35x35 S102
3x36 3.36x36 M103
3x39 3.39x39 S106
TM6
6x48 6.48x48 W236
TM7
7x35 7.36x35 K267
7x38 7.39x38 I270
7x41 7.42x41 A273
7x42 7.43x42 F274
7x45 7.45x45 S276
7x46 7.46x46 S277