CHEMBL292275


SMILES CCOC(=O)N1CCN(CCCOc2ccc(C(=O)/C=C/c3ccc(OC)cc3)cc2)CC1
InChIKey BYKHDCPMWIUHPJ-VGOFMYFVSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 10
Molecular weight (Da) 452.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H3 HRH3 Rat Histamine A pKi 8.14 8.14 8.14 ChEMBL
H2 HRH2 Human Histamine A pKi 5.17 5.17 5.17 ChEMBL
H1 HRH1 Human Histamine A pKi 6.21 6.21 6.21 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database