R214127
| SMILES | O=C(c1ccc2c(c1)cc1c(n2)OCCC1)Cc1ccccc1 |
| InChIKey | HXUSRWUBSYSWII-UHFFFAOYSA-N |
Chemical properties
| Hydrogen bond acceptors | 3 |
| Hydrogen bond donors | 0 |
| Rotatable bonds | 3 |
| Molecular weight (Da) | 303.1 |
Drug properties
| Molecular type | Small molecule |
| Physiological/Surrogate | Surrogate |
| Approved drug | No |
Database connections
Sankey plot
Compound is not listed as a drug.
Bioactivities
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| mGlu1 | GRM1 | Human | Metabotropic glutamate | C | pKd | 9.0 | 9.0 | 9.0 | Guide to Pharmacology |
| mGlu1 | GRM1 | Rat | Metabotropic glutamate | C | pKi | 8.9 | 8.9 | 8.9 | Guide to Pharmacology |
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| mGlu1 | GRM1 | Human | Metabotropic glutamate | C | pIC50 | 7.98 | 7.98 | 7.98 | Guide to Pharmacology |
| mGlu1 | GRM1 | Rat | Metabotropic glutamate | C | pIC50 | 8.22 | 8.22 | 8.22 | ChEMBL |
| mGlu1 | GRM1 | Human | Metabotropic glutamate | C | pIC50 | 7.85 | 7.85 | 7.85 | ChEMBL |