CHEMBL247664


SMILES COc1cc2c(cc1OC)CN(Cc1ccc(OC)c3oc(C(=O)NCC(C)(C)N)cc13)CC2
InChIKey JYEPTVGXWUQMKF-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 2
Rotatable bonds 8
Molecular weight (Da) 467.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2B ADA2B Human Adrenoceptors A pKi 5.81 5.81 5.81 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 8.38 8.38 8.38 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 6.85 6.85 6.85 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 6.85 6.85 6.85 PDSP Ki database
α2B ADA2B Human Adrenoceptors A pKi 5.81 5.81 5.81 PDSP Ki database
α2C ADA2C Human Adrenoceptors A pKi 8.38 8.38 8.38 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database