CHEMBL247665


SMILES COc1cc2c(cc1OC)CN(Cc1ccc(OC)c3oc(C(=O)N4CCC(N5CCCC5)CC4)cc13)CC2
InChIKey IVEMQVDPOPYVKY-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 0
Rotatable bonds 7
Molecular weight (Da) 533.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2B ADA2B Human Adrenoceptors A pKi 5.87 5.87 5.87 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 8.46 8.46 8.46 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 6.73 6.73 6.73 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 6.73 6.73 6.73 PDSP Ki database
α2B ADA2B Human Adrenoceptors A pKi 5.87 5.87 5.87 PDSP Ki database
α2C ADA2C Human Adrenoceptors A pKi 8.46 8.46 8.46 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database