R(-)amphetamine
| SMILES | C[C@H](Cc1ccccc1)N |
| InChIKey | KWTSXDURSIMDCE-MRVPVSSYSA-N |
Chemical properties
| Hydrogen bond acceptors | 1 |
| Hydrogen bond donors | 1 |
| Rotatable bonds | 2 |
| Molecular weight (Da) | 135.1 |
Drug properties
| Molecular type | Small molecule |
| Physiological/Surrogate | Surrogate |
| Approved drug | Yes |
Database connections
Sankey plot
Compound is not listed as a drug.
Bioactivities
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| β2 | ADRB2 | Human | Adrenoceptors | A | pKi | 5.0 | 5.0 | 5.0 | PDSP Ki database |
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| TA1 | TAAR1 | Human | Trace amine | A | pEC50 | 6.4 | 6.4 | 6.4 | Guide to Pharmacology |
| TA1 | TAAR1 | Rat | Trace amine | A | pEC50 | 6.5 | 6.6 | 6.7 | Guide to Pharmacology |
| TA1 | TAAR1 | Mouse | Trace amine | A | pEC50 | 5.3 | 6.25 | 7.2 | Guide to Pharmacology |
| TA1 | TAAR1 | Rhesus macaque | Trace amine | A | pEC50 | 5.73 | 5.73 | 5.73 | ChEMBL |
| TA1 | TAAR1 | Rat | Trace amine | A | pEC50 | 5.85 | 6.66 | 7.47 | ChEMBL |
| TA1 | TAAR1 | Human | Trace amine | A | pEC50 | 5.77 | 6.07 | 6.6 | ChEMBL |
| TA1 | TAAR1 | Mouse | Trace amine | A | pEC50 | 5.3 | 6.5 | 7.19 | ChEMBL |
| TA1 | TAAR1 | Rat | Trace amine | A | pEC50 | 8.13 | 8.13 | 8.13 | Drug Central |
| TA1 | TAAR1 | Mouse | Trace amine | A | pEC50 | 8.14 | 8.14 | 8.14 | Drug Central |
| TA1 | TAAR1 | Rhesus macaque | Trace amine | A | pEC50 | 8.24 | 8.24 | 8.24 | Drug Central |
| TA1 | TAAR1 | Human | Trace amine | A | pEC50 | 8.18 | 8.18 | 8.18 | Drug Central |