GPCRdb

CHEMBL292274

Agent/drug
Bioactivity

CHEMBL292274

SMILES	CN(C)[C@H]1CCc2ccc3[nH]ccc3c2C1
InChIKey	HENBLLXAHPTGHX-NSHDSACASA-N

Chemical Properties

Hydrogen bond acceptors	1
Hydrogen bond donors	1
Rotatable bonds	1
Molecular weight (Da)	214.1

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

5-HT_1A	5HT1A	Rat	5-Hydroxytryptamine	A	pKi	6.72	6.79	6.86	ChEMBL
5-HT_1B	5HT1B	Human	5-Hydroxytryptamine	A	pKi	5.77	5.77	5.77	ChEMBL
5-HT_1D	5HT1D	Human	5-Hydroxytryptamine	A	pKi	6.64	6.64	6.64	ChEMBL
D₂	DRD2	Rat	Dopamine	A	pKi	5.80	6.11	6.42	ChEMBL

Showing 1 to 4 of 4 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

5-HT_1A	5HT1A	Rat	5-Hydroxytryptamine	A	pIC50	6.61	6.61	6.61	ChEMBL
D₁	DRD1	Rat	Dopamine	A	pIC50	4.54	4.54	4.54	ChEMBL
D₂	DRD2	Rat	Dopamine	A	pIC50	5.02	5.02	5.02	ChEMBL

Showing 1 to 3 of 3 entries

CHEMBL292274

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.