CHEMBL296506


SMILES COc1ccccc1N1CCN(CNC(=O)c2cccc(C)c2)CC1
InChIKey JIXQPDNGVCMIOH-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 339.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 7.89 8.08 8.17 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.61 5.61 5.61 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.61 5.85 6.08 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pEC50 7.89 7.89 7.89 ChEMBL