revefenacin


SMILES O=C(Nc1ccccc1c1ccccc1)OC1CCN(CC1)CCN(C(=O)c1ccc(cc1)CN1CCC(CC1)C(=O)N)C
InChIKey FYDWDCIFZSGNBU-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 10
Molecular weight (Da) 597.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug Yes

Database connections

Sankey plot

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 9.52 9.52 9.52 Guide to Pharmacology
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 9.75 9.75 9.75 Guide to Pharmacology
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 9.26 9.26 9.26 Guide to Pharmacology
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 8.2 8.2 8.2 Guide to Pharmacology
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 8.03 8.03 8.03 Drug Central
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 8.02 8.02 8.02 Drug Central
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 8.01 8.01 8.01 Drug Central
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 8.03 8.03 8.03 Drug Central
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 8.09 8.09 8.09 Drug Central
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 9.38 9.38 9.38 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database