CHEMBL297428


SMILES CC1C2Cc3ccc(C(N)=O)cc3C1(C)CCN2CC1CC1
InChIKey FAVQVALXVLMHLE-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 298.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ A0A286XTF2 Guinea pig Opioid A pKi 8.08 8.08 8.08 ChEMBL
κ OPRK Guinea pig Opioid A pKi 9.28 9.28 9.28 ChEMBL
δ OPRD Human Opioid A pKi 8.28 8.61 9.28 ChEMBL
κ OPRK Human Opioid A pKi 10.22 10.22 10.22 ChEMBL
μ OPRM Human Opioid A pKi 9.51 9.51 9.51 ChEMBL
δ OPRD Human Opioid A pKi 8.28 8.28 8.28 PDSP Ki database
κ OPRK Human Opioid A pKi 10.22 10.22 10.22 PDSP Ki database
μ OPRM Human Opioid A pKi 9.51 9.51 9.51 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Human Opioid A pEC50 8.06 8.34 8.62 ChEMBL
μ OPRM Human Opioid A pIC50 7.82 7.82 7.82 ChEMBL
μ OPRM Human Opioid A pEC50 8.31 8.66 9.0 ChEMBL