Ro 63-0563


SMILES CNc1cc(cc(n1)NC)NS(=O)(=O)c1ccc(cc1)N
InChIKey PTFNKZLSFWJYFJ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 4
Rotatable bonds 5
Molecular weight (Da) 307.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 7.9 8.15 8.4 Guide to Pharmacology
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKd 8.3 8.3 8.3 Guide to Pharmacology
5-HT6 5HT6R Rat 5-Hydroxytryptamine A pKi 7.8 7.9 8.0 Guide to Pharmacology
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.29 7.74 7.92 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database