CHEMBL300152


SMILES CC(CN1CCN(c2cc(Cl)ccc2Cl)CC1)N1C(=O)CC2(CCCC2)CC1=O
InChIKey RPADCEVSPXUEKK-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 437.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1D ADA1D Rat Adrenoceptors A pKi 9.39 9.39 9.39 ChEMBL
α1A ADA1A Rat Adrenoceptors A pKi 6.73 6.73 6.73 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 6.82 6.83 6.83 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.68 6.68 6.68 ChEMBL
α1B ADA1B Human Adrenoceptors A pKi 7.88 7.88 7.88 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database