GPCRdb

CHEMBL297428

Agent/drug
Bioactivity

CHEMBL297428

SMILES	CC1C2Cc3ccc(C(N)=O)cc3C1(C)CCN2CC1CC1
InChIKey	FAVQVALXVLMHLE-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	2
Hydrogen bond donors	1
Rotatable bonds	3
Molecular weight (Da)	298.2

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

δ	A0A286XTF2	Guinea pig	Opioid	A	pKi	8.08	8.08	8.08	ChEMBL
δ	OPRD	Human	Opioid	A	pKi	8.28	8.61	9.28	ChEMBL
δ	OPRD	Human	Opioid	A	pKi	8.28	8.28	8.28	PDSP Ki database
κ	OPRK	Guinea pig	Opioid	A	pKi	9.28	9.28	9.28	ChEMBL
κ	OPRK	Human	Opioid	A	pKi	10.22	10.22	10.22	ChEMBL
κ	OPRK	Human	Opioid	A	pKi	10.22	10.22	10.22	PDSP Ki database
μ	OPRM	Human	Opioid	A	pKi	9.51	9.51	9.51	ChEMBL
μ	OPRM	Human	Opioid	A	pKi	9.51	9.51	9.51	PDSP Ki database

Showing 1 to 8 of 8 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

κ	OPRK	Human	Opioid	A	pEC50	8.06	8.34	8.62	ChEMBL
μ	OPRM	Human	Opioid	A	pIC50	7.82	7.82	7.82	ChEMBL
μ	OPRM	Human	Opioid	A	pEC50	8.31	8.66	9.00	ChEMBL

Showing 1 to 3 of 3 entries

CHEMBL297428

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.