CHEMBL302468


SMILES N[C@@H](C(=O)N1CCN(CCCOc2ccc(C(=O)C3CC3)cc2)CC1)c1ccccc1
InChIKey PIIKAHNRVYTSPK-HSZRJFAPSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 9
Molecular weight (Da) 421.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H3 HRH3 Rat Histamine A pKi 7.56 7.56 7.56 ChEMBL
H2 HRH2 Human Histamine A pKi 4.61 4.61 4.61 ChEMBL
H1 HRH1 Human Histamine A pKi 5.34 5.34 5.34 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database