GPCRdb

CHEMBL299879

Agent/drug
Bioactivity

CHEMBL299879

SMILES	O=[N+]([O-])c1ccccc1S(=O)(=O)NC[C@H]1CC[C@H](CNCC2CCc3ccccc3C2)CC1
InChIKey	ISSSVYKMIIAPTH-YGQOYYDZSA-N

Chemical Properties

Hydrogen bond acceptors	5
Hydrogen bond donors	2
Rotatable bonds	9
Molecular weight (Da)	471.2

Database connections

ChEMBL_compound_ids ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

α_2C	ADA2C	Human	Adrenoceptors	A	pKi	7.00	7.00	7.00	ChEMBL
D₂	DRD2	Human	Dopamine	A	pKi	7.20	7.20	7.20	ChEMBL
Y₁	NPY1R	Rat	Neuropeptide Y	A	pKi	4.66	4.66	4.66	ChEMBL
Y₁	NPY1R	Human	Neuropeptide Y	A	pKi	4.79	4.79	4.79	ChEMBL
Y₅	NPY5R	Human	Neuropeptide Y	A	pKi	8.10	8.10	8.10	ChEMBL
Y₅	NPY5R	Rat	Neuropeptide Y	A	pKi	7.75	7.75	7.75	ChEMBL

Showing 1 to 6 of 6 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

TSH	TSHR	Human	Glycoprotein hormone	A	Potency	5.00	5.00	5.00	ChEMBL

Showing 1 to 1 of 1 entry

CHEMBL299879

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.