RWJ-351647


SMILES Clc1cc(ccc1C(=O)N1C[C@H]2COCCN2Cc2c1cccc2)NC(=O)c1ccccc1c1ccccc1
InChIKey TYWBAYRNYLDJBB-VWLOTQADSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 537.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
V1A V1AR Human Vasopressin and oxytocin A pKi 7.6 7.6 7.6 Guide to Pharmacology
V2 V2R Human Vasopressin and oxytocin A pKi 9.0 9.0 9.0 Guide to Pharmacology
V2 V2R Human Vasopressin and oxytocin A pKi 8.4 8.73 9.05 ChEMBL
V1A V1AR Human Vasopressin and oxytocin A pKi 6.22 6.92 7.62 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database