GPCRdb

CHEMBL301242

Agent/drug
Bioactivity

CHEMBL301242

SMILES	O=C(NCCCCN1CCN(c2cccc(Cl)c2Cl)CC1)c1cccc2c1-c1ccccc1C2=O
InChIKey	WOWYFQWPMWYJNL-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	4
Hydrogen bond donors	1
Rotatable bonds	7
Molecular weight (Da)	507.1

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

D₂	DRD2	Rat	Dopamine	A	pKi	6.82	6.94	7.05	ChEMBL
D₂	DRD2	Human	Dopamine	A	pKi	7.05	7.30	7.71	ChEMBL
D₃	DRD3	Rat	Dopamine	A	pKi	8.80	8.82	8.85	ChEMBL
D₃	DRD3	Human	Dopamine	A	pKi	8.31	8.52	8.85	ChEMBL
D₄	DRD4	Human	Dopamine	A	pKi	5.73	5.80	5.95	ChEMBL

Showing 1 to 5 of 5 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

D₂	DRD2	Human	Dopamine	A	pIC50	7.45	7.64	7.84	ChEMBL

Showing 1 to 1 of 1 entry

CHEMBL301242

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.