CHEMBL3040324


SMILES c1ccc(Cc2nc3c(c(Nc4ccccc4)n2)CCNCC3)cc1
InChIKey QEAYWRGPVOISMK-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 4
Molecular weight (Da) 330.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1A ADA1A Human Adrenoceptors A pIC50 5.86 5.86 5.86 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pIC50 5.81 5.81 5.81 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pIC50 7.05 7.05 7.05 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pIC50 7.43 7.43 7.43 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pIC50 8.7 8.7 8.7 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pEC50 7.7 7.7 7.7 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pIC50 6.4 6.4 6.4 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pIC50 8.57 8.57 8.57 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pEC50 8.21 8.21 8.21 ChEMBL
D3 DRD3 Human Dopamine A pIC50 6.57 6.57 6.57 ChEMBL
D2 DRD2 Human Dopamine A pIC50 6.83 6.83 6.83 ChEMBL