CHEMBL3040803


SMILES COc1ccc2c(c1OCCNC[C@H]1COc3ccccc3O1)NCC2
InChIKey GENVWLSAPICTPF-HNNXBMFYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 7
Molecular weight (Da) 356.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1D ADA1D Rat Adrenoceptors A pKd 8.62 8.62 8.62 ChEMBL
α1B ADA1B Rat Adrenoceptors A pKd 9.08 9.08 9.08 ChEMBL
α1B ADA1B Human Adrenoceptors A pKi 7.45 7.45 7.45 ChEMBL
α1A ADA1A Rat Adrenoceptors A pKd 8.03 8.23 8.44 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 8.42 8.42 8.42 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 7.89 7.89 7.89 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 6.96 6.96 6.96 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database