CHEMBL305029


SMILES CC(C)Oc1ccccc1N1CCN(Cc2ccc(CN3CCCCC3=O)s2)CC1
InChIKey INRFQTYFEDZXNB-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 7
Molecular weight (Da) 427.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Human Adrenoceptors A pKi 6.38 6.38 6.38 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 9.52 9.52 9.52 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 7.75 7.75 7.75 ChEMBL
D2 DRD2 Rat Dopamine A pKi 7.17 7.17 7.17 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 8.51 8.51 8.51 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database