GPCRdb

CHEMBL303855

Agent/drug
Bioactivity

CHEMBL303855

SMILES	C=CCN1CC(C)N(C(c2ccc(C(=O)N(CC)CC)cc2)c2cccc(O)c2)CC1C
InChIKey	LBLDMHBSVIVJPM-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	4
Hydrogen bond donors	1
Rotatable bonds	8
Molecular weight (Da)	435.3

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

δ	OPRD	Human	Opioid	A	pKi	11.00	11.00	11.00	PDSP Ki database
κ	OPRK	Human	Opioid	A	pKi	7.77	7.77	7.77	PDSP Ki database
μ	OPRM	Human	Opioid	A	pKi	7.59	7.59	7.59	PDSP Ki database

Showing 1 to 3 of 3 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

δ	OPRD	Mouse	Opioid	A	pIC50	9.04	9.37	9.70	ChEMBL
μ	OPRM	Rat	Opioid	A	pIC50	7.33	7.33	7.33	ChEMBL

Showing 1 to 2 of 2 entries

CHEMBL303855

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.