satavaptan


SMILES CCOc1ccc2c(c1)[C@@]1(CC[C@H](CC1)OCCN1CCOCC1)C(=O)N2S(=O)(=O)c1ccc(cc1OC)C(=O)NC(C)(C)C
InChIKey QKXJWFOKVQWEDZ-VCCCEUOBSA-N

Chemical properties

Hydrogen bond acceptors 9
Hydrogen bond donors 1
Rotatable bonds 10
Molecular weight (Da) 643.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug Yes

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
V1A V1AR Human Vasopressin and oxytocin A pKi 6.5 6.5 6.5 Guide to Pharmacology
V1B V1BR Human Vasopressin and oxytocin A pKi 4.3 4.3 4.3 Guide to Pharmacology
V2 V2R Human Vasopressin and oxytocin A pKi 8.4 8.85 9.3 Guide to Pharmacology
V1A V1AR Human Vasopressin and oxytocin A pKi 5.53 6.03 6.52 ChEMBL
V2 V2R Rat Vasopressin and oxytocin A pKi 9.3 9.3 9.3 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database