SB 207710


SMILES CCCCN1CCC(CC1)COC(=O)c1cc(I)c(c2c1OCCO2)N
InChIKey FCKKCDRMGKXQDK-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 474.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT4 5HT4R Human 5-Hydroxytryptamine A pKi 10.1 10.2 10.3 Guide to Pharmacology
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 5.3 5.4 5.5 Guide to Pharmacology
5-HT4 5HT4R Rat 5-Hydroxytryptamine A pKd 9.52 9.52 9.52 ChEMBL
5-HT4 5HT4R Human 5-Hydroxytryptamine A pKi 8.66 8.66 8.66 ChEMBL
5-HT4 5HT4R Guinea pig 5-Hydroxytryptamine A pKi 9.7 9.7 9.7 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT4 5HT4R Human 5-Hydroxytryptamine A pEC50 7.9 7.9 7.9 ChEMBL