SB-436811


SMILES CN(CCCOc1ccc(cc1)CN1CC[C@@H](C1)NC(=O)c1ccc(c(c1)Cl)Cl)C
InChIKey AMSSIFVGNFEEFU-IBGZPJMESA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 9
Molecular weight (Da) 449.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
UT UR2R Rat Urotensin A pKi 6.7 6.7 6.7 Guide to Pharmacology
UT UR2R Rhesus macaque Urotensin A pKi 6.6 6.6 6.6 ChEMBL
UT UR2R Rat Urotensin A pKi 5.5 7.0 8.49 ChEMBL
UT UR2R Human Urotensin A pKi 6.6 6.67 6.7 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
UT UR2R Human Urotensin A pIC50 6.77 6.79 6.8 ChEMBL