CHEMBL260994


SMILES O=C1Nc2ccccc2C1CCCCN1CCN(c2ccc(Cl)cc2)CC1
InChIKey JAOXKCOCADFHNG-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 383.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 8.15 8.79 9.42 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 7.38 7.38 7.38 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 5.75 5.75 5.75 ChEMBL
D1 DRD1 Human Dopamine A pKi 5.62 5.62 5.62 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.24 6.24 6.24 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.16 6.16 6.16 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.76 7.76 7.76 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.02 6.02 6.02 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database