SB656104


SMILES Clc1ccc(cc1)OC1CCN(CC1)CC[C@H]1CCCN1S(=O)(=O)c1ccc2c(c1)[nH]cc2
InChIKey QEGMGDYIJDZJCI-OAQYLSRUSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 487.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 8.7 8.7 8.7 Guide to Pharmacology
5-HT7 5HT7R Rat 5-Hydroxytryptamine A pKi 8.7 8.7 8.7 ChEMBL
5-HT5A 5HT5A Human 5-Hydroxytryptamine A pKi 6.74 6.76 6.78 ChEMBL
5-HT4 5HT4R Human 5-Hydroxytryptamine A pKi 5.72 5.72 5.72 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 7.6 7.6 7.6 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 8.49 8.65 8.7 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 6.66 6.66 6.66 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.07 6.07 6.07 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.25 6.42 6.6 ChEMBL
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 6.2 6.2 6.2 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.2 7.2 7.2 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 7.04 7.04 7.04 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.57 6.57 6.57 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database