SB-706375
| SMILES | COc1cc(c(cc1OC)Br)S(=O)(=O)Nc1ccc(c(c1)O[C@@H]1CCN(C1)C)C(F)(F)F |
| InChIKey | BPOWQJYAMDEAFF-CYBMUJFWSA-N |
Chemical properties
| Hydrogen bond acceptors | 6 |
| Hydrogen bond donors | 1 |
| Rotatable bonds | 7 |
| Molecular weight (Da) | 538.0 |
Drug properties
| Molecular type | Small molecule |
| Physiological/Surrogate | Surrogate |
| Approved drug | No |
Database connections
Sankey plot
Compound is not listed as a drug.
Bioactivities
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| UT | UR2R | Human | Urotensin | A | pKi | 8.0 | 8.0 | 8.0 | Guide to Pharmacology |
| UT | UR2R | Mouse | Urotensin | A | pKi | 7.7 | 7.7 | 7.7 | Guide to Pharmacology |
| UT | UR2R | Rat | Urotensin | A | pKi | 7.7 | 7.7 | 7.7 | Guide to Pharmacology |
| UT | UR2R | Human | Urotensin | A | pKi | 8.1 | 8.18 | 8.27 | ChEMBL |
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| UT | UR2R | Human | Urotensin | A | pIC50 | 7.85 | 8.06 | 8.22 | ChEMBL |
| UT | UR2R | Rat | Urotensin | A | pIC50 | 7.47 | 7.47 | 7.47 | ChEMBL |