SB 714786


SMILES Cc1ccc2c(n1)cccc2OCCN1CCN(CC1)Cc1cccc2c1nccc2
InChIKey RMCSKUADBRROSI-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 412.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.5 6.5 6.5 Guide to Pharmacology
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 6.7 6.7 6.7 Guide to Pharmacology
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 9.1 9.1 9.1 Guide to Pharmacology
5-HT1F 5HT1F Human 5-Hydroxytryptamine A pKi 5.7 5.7 5.7 ChEMBL
5-HT5A 5HT5A Human 5-Hydroxytryptamine A pKi 5.5 5.5 5.5 ChEMBL
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 6.7 6.7 6.7 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 9.1 9.1 9.1 ChEMBL
α1B ADA1B Human Adrenoceptors A pKi 6.0 6.0 6.0 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.3 6.3 6.3 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 5.9 5.9 5.9 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 5.5 5.5 5.5 ChEMBL
β2 ADRB2 Human Adrenoceptors A pKi 5.7 5.7 5.7 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.0 6.0 6.0 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.5 6.5 6.5 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.5 5.5 5.5 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database