SCH 37370
| SMILES | Clc1ccc2c(c1)CCc1c(C2=C2CCN(CC2)C(=O)C)nccc1 |
| InChIKey | FLTBEMVEAFMWDD-UHFFFAOYSA-N |
Chemical properties
| Hydrogen bond acceptors | 2 |
| Hydrogen bond donors | 0 |
| Rotatable bonds | 0 |
| Molecular weight (Da) | 352.1 |
Drug properties
| Molecular type | Small molecule |
| Physiological/Surrogate | Surrogate |
| Approved drug | No |
Database connections
Sankey plot
Compound is not listed as a drug.
Bioactivities
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| H1 | HRH1 | Rat | Histamine | A | pKi | 6.5 | 6.5 | 6.5 | ChEMBL |
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| PAF | PTAFR | Human | Platelet-activating factor | A | pIC50 | 6.2 | 6.2 | 6.2 | Guide to Pharmacology |
| PAF | PTAFR | Human | Platelet-activating factor | A | pIC50 | 6.08 | 6.14 | 6.21 | ChEMBL |
| H1 | HRH1 | Human | Histamine | A | pIC50 | 7.0 | 7.0 | 7.0 | ChEMBL |