SIB-1757


SMILES Cc1ccc(c(n1)/N=N/c1ccccc1)O
InChIKey LOCPVWIREQIGNQ-CCEZHUSRSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 2
Molecular weight (Da) 213.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu5 GRM5 Human Metabotropic glutamate C pKi 6.43 6.43 6.43 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu5 GRM5 Human Metabotropic glutamate C pIC50 6.0 6.2 6.4 Guide to Pharmacology
M1 ACM1 Rat Acetylcholine (muscarinic) A Potency 5.35 5.35 5.35 ChEMBL
mGlu5 GRM5 Rat Metabotropic glutamate C pIC50 5.93 5.93 5.93 ChEMBL
mGlu5 GRM5 Human Metabotropic glutamate C pIC50 6.43 6.43 6.43 ChEMBL