SKF-83566


SMILES CN1CCc2c(C(C1)c1ccccc1)cc(c(c2)Br)O
InChIKey XFTVOHWWEQGXLS-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 1
Molecular weight (Da) 331.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Human Dopamine A pKi 9.5 9.5 9.5 Guide to Pharmacology
D5 DRD5 Human Dopamine A pKi 9.4 9.4 9.4 Guide to Pharmacology
D5 DRD5 Human Dopamine A pKi 8.4 8.6 8.76 ChEMBL
D1 DRD1 Human Dopamine A pKi 9.52 9.52 9.52 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.87 5.87 5.87 ChEMBL
5-HT2C K7GSR7 Pig 5-Hydroxytryptamine A pKi 7.94 7.96 8.0 PDSP Ki database
5-HT5A 5HT5A Rat 5-Hydroxytryptamine A pKi 6.0 6.0 6.0 PDSP Ki database
D5 DRD5 Human Dopamine A pKi 9.4 9.4 9.4 PDSP Ki database
D1 DRD1 Human Dopamine A pKi 9.52 9.52 9.52 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database