SNC80


SMILES C=CCN1C[C@H](C)N(C[C@H]1C)[C@@H](c1cccc(c1)OC)c1ccc(cc1)C(=O)N(CC)CC
InChIKey KQWVAUSXZDRQPZ-UMTXDNHDSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 9
Molecular weight (Da) 449.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 7.2 7.2 7.2 Guide to Pharmacology
κ OPRK Rat Opioid A pKi 5.45 5.45 5.45 ChEMBL
κ OPRK Mouse Opioid A pKi 5.56 5.71 5.87 ChEMBL
μ OPRM Mouse Opioid A pKi 5.62 5.89 6.16 ChEMBL
δ OPRD Mouse Opioid A pKi 7.78 8.71 9.15 ChEMBL
κ OPRK Guinea pig Opioid A pKi 4.93 5.15 5.45 ChEMBL
κ OPRK Guinea pig Opioid A pKd 6.2 6.2 6.2 ChEMBL
μ OPRM Rat Opioid A pKi 5.09 5.68 5.89 ChEMBL
δ OPRD Human Opioid A pKi 8.77 8.87 8.92 ChEMBL
δ OPRD Human Opioid A pKd 6.2 6.2 6.2 ChEMBL
κ OPRK Human Opioid A pKi 5.38 5.43 5.45 ChEMBL
μ OPRM Human Opioid A pKi 5.89 6.17 6.45 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Rat Opioid A pIC50 5.44 5.44 5.44 ChEMBL
μ OPRM Mouse Opioid A pIC50 5.22 5.22 5.22 ChEMBL
δ OPRD Mouse Opioid A pIC50 6.19 7.99 9.1 ChEMBL
κ OPRK Guinea pig Opioid A pIC50 5.15 5.46 5.9 ChEMBL
μ OPRM Rat Opioid A pIC50 5.03 5.37 5.61 ChEMBL
δ OPRD Human Opioid A pEC50 6.12 8.03 8.77 ChEMBL
δ OPRD Human Opioid A pIC50 7.31 8.55 8.89 ChEMBL
κ OPRK Human Opioid A pIC50 5.61 5.61 5.61 ChEMBL
κ OPRK Human Opioid A pEC50 5.28 5.28 5.28 ChEMBL
μ OPRM Human Opioid A pEC50 9.85 9.85 9.85 ChEMBL
μ OPRM Human Opioid A pIC50 5.32 6.11 6.5 ChEMBL