TAN-67


SMILES CN1CC[C@]2([C@H](C1)Cc1c(C2)nc2c(c1)cccc2)c1cccc(c1)O
InChIKey LEPBHAAYNPPRRA-WMZHIEFXSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 1
Molecular weight (Da) 344.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Mouse Opioid A pKi 6.51 6.51 6.51 ChEMBL
μ OPRM Mouse Opioid A pKi 6.55 6.88 7.22 ChEMBL
δ OPRD Mouse Opioid A pKi 8.84 9.24 9.64 ChEMBL
κ OPRK Guinea pig Opioid A pKi 6.13 6.13 6.13 ChEMBL
μ OPRM Rat Opioid A pKi 6.55 6.55 6.55 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Mouse Opioid A pIC50 8.44 8.44 8.44 Guide to Pharmacology
δ OPRD Human Opioid A pEC50 8.85 9.05 9.15 ChEMBL
MRGPRX2 MRGX2 Human A orphans A pEC50 5.74 5.74 5.74 Guide to Pharmacology