tecalcet


SMILES COc1cccc(c1)[C@H](NCCCc1ccccc1Cl)C
InChIKey ZVQUCWXZCKWZBP-CQSZACIVSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 303.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Structure pdb 7SIL
Ligand site mutations CaS

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CaS CASR Human Calcium-sensing C pKd 6.5 6.5 6.5 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CaS CASR Human Calcium-sensing C pKB 6.2 6.4 6.6 Guide to Pharmacology
CaS CASR Human Calcium-sensing C pEC50 6.71 6.97 7.1 ChEMBL