TRH
| SMILES | None |
| InChIKey | XNSAINXGIQZQOO-SRVKXCTJSA-N |
| Sequence | XHP |
Chemical properties
| Hydrogen bond acceptors | None |
| Hydrogen bond donors | None |
| Rotatable bonds | None |
| Molecular weight (Da) |
Drug properties
| Molecular type | Peptide |
| Physiological/Surrogate | Endogenous |
| Approved drug | Yes |
Database connections
Sankey plot
, 'sankey_.png');){kind=link}
, 'sankey_.jpg');){kind=link}
Bioactivities
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| TRH1 | TRHR | Rat | Thyrotropin-releasing hormone | A | pKi | 7.37 | 7.54 | 7.7 | ChEMBL |
| TRH1 | TRFR | Human | Thyrotropin-releasing hormone | A | pKi | 7.7 | 7.7 | 7.7 | ChEMBL |
| TRH1 | TRFR | Human | Thyrotropin-releasing hormone | A | pKi | 8.11 | 8.11 | 8.11 | Drug Central |
| TRH1 | TRHR | Mouse | Thyrotropin-releasing hormone | A | pKi | 8.1 | 8.1 | 8.1 | Drug Central |
| motilin | Q9R297 | Rat | Motilin | A | pKi | 8.1 | 8.1 | 8.1 | Drug Central |
| TRH1 | TRHR | Mouse | Thyrotropin-releasing hormone | A | pKi | 7.64 | 7.82 | 8.0 | ChEMBL |
| TRH1 | TRHR | Rat | Thyrotropin-releasing hormone | A | pKi | 8.11 | 8.11 | 8.11 | Drug Central |
| TRH1 | TRHR | Rat | Thyrotropin-releasing hormone | A | pKi | 7.4 | 7.4 | 7.4 | Guide to Pharmacology |
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| TRH1 | TRHR | Rat | Thyrotropin-releasing hormone | A | pEC50 | 8.52 | 8.52 | 8.52 | ChEMBL |
| TRH1 | TRFR | Human | Thyrotropin-releasing hormone | A | pEC50 | 8.52 | 8.52 | 8.52 | ChEMBL |
| TRH1 | TRHR | Mouse | Thyrotropin-releasing hormone | A | pEC50 | 8.49 | 8.99 | 9.31 | ChEMBL |
| TRH1 | TRHR | Mouse | Thyrotropin-releasing hormone | A | pIC50 | 7.58 | 8.09 | 8.59 | ChEMBL |