CHEMBL1171006


SMILES O=C(O)c1ccccc1Oc1c(F)cc(C(F)(F)F)cc1NS(=O)(=O)c1ccc(Cl)cc1
InChIKey AHVWEICLWNKDKM-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 6
Molecular weight (Da) 489.0

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CCR2 CCR2 Mouse Chemokine A pKi 6.6 6.6 6.6 ChEMBL
CCR1 CCR1 Human Chemokine A pKi 6.9 6.9 6.9 ChEMBL
CCR2 CCR2 Human Chemokine A pKi 4.9 6.53 7.5 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database