GPCRdb

CHEMBL3138992

Agent/drug
Bioactivity

CHEMBL3138992

SMILES	C[C@H](NC(=O)[C@H]1CCCCN1CCOc1ccccc1)c1ccc(C(=O)O)cc1
InChIKey	ADSVKUMNMQPBKC-LAUBAEHRSA-N

Chemical Properties

Hydrogen bond acceptors	4
Hydrogen bond donors	2
Rotatable bonds	8
Molecular weight (Da)	396.2

Database connections

ChEMBL_compound_ids ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

EP₂	PE2R2	Human	Prostanoid	A	pKi	5.81	5.85	5.92	ChEMBL
EP₄	PE2R4	Human	Prostanoid	A	pKi	7.27	7.31	7.39	ChEMBL

Showing 1 to 2 of 2 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

EP₂	PE2R2	Human	Prostanoid	A	pIC50	5.79	5.79	5.79	ChEMBL
EP₄	PE2R4	Rat	Prostanoid	A	pIC50	7.82	7.82	7.82	ChEMBL
EP₄	PE2R4	Human	Prostanoid	A	pIC50	6.90	7.48	8.25	ChEMBL

Showing 1 to 3 of 3 entries

CHEMBL3138992

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV 0

Database connections

ChEMBL_compound_ids ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.