CHEMBL285843


SMILES NC(CCP(=O)(O)O)C(=O)O
InChIKey DDOQBQRIEWHWBT-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 4
Rotatable bonds 4
Molecular weight (Da) 183.0

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu6 GRM6 Rat Metabotropic glutamate C pKi 6.4 6.4 6.4 PDSP Ki database
mGlu4 GRM4 Rat Metabotropic glutamate C pKi 6.4 6.4 6.4 PDSP Ki database
mGlu2 GRM2 Rat Metabotropic glutamate C pKi 5.0 5.0 5.0 PDSP Ki database
mGlu8 GRM8 Rat Metabotropic glutamate C pKi 5.57 5.74 5.9 PDSP Ki database
mGlu6 GRM6 Human Metabotropic glutamate C pKi 6.05 6.05 6.05 PDSP Ki database
mGlu7 GRM7 Human Metabotropic glutamate C pKi 5.0 5.0 5.0 PDSP Ki database
mGlu8 GRM8 Human Metabotropic glutamate C pKi 6.4 6.4 6.4 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu6 GRM6 Rat Metabotropic glutamate C pEC50 6.0 6.0 6.0 ChEMBL
mGlu8 GRM8 Human Metabotropic glutamate C pIC50 8.29 8.29 8.29 ChEMBL
mGlu6 GRM6 Human Metabotropic glutamate C pEC50 6.55 6.55 6.55 ChEMBL
mGlu4 GRM4 Human Metabotropic glutamate C pEC50 6.48 6.48 6.48 ChEMBL