CHEMBL288199
SMILES | COc1cc(N)c(Cl)cc1C(=O)O[C@@H]1CN2CCC1CC2 |
InChIKey | HBNLYLTXNASDDE-CQSZACIVSA-N |
Chemical properties
Hydrogen bond acceptors | 5 |
Hydrogen bond donors | 1 |
Rotatable bonds | 3 |
Molecular weight (Da) | 310.1 |
Drug properties
Molecular type | Small molecule |
Physiological/Surrogate | Surrogate |
Approved drug | No |
Database connections
Sankey plot
Compound is not listed as a drug.
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
5-HT4 | 5HT4R | Rat | 5-Hydroxytryptamine | A | pKi | 7.04 | 7.04 | 7.04 | ChEMBL |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
5-HT4 | 5HT4R | Guinea pig | 5-Hydroxytryptamine | A | pEC50 | 6.82 | 6.82 | 6.82 | ChEMBL |
5-HT4 | 5HT4R | Guinea pig | 5-Hydroxytryptamine | A | pIC50 | 6.35 | 6.35 | 6.35 | ChEMBL |