CHEMBL29067
| SMILES | CCOC(=O)C1=C(c2ccc(-n3c(C)nc4cnccc43)cc2)NC(C)=C(C(=O)Nc2ccccn2)C1c1ccccc1Cl |
| InChIKey | ODRYSCQFUGFOSU-UHFFFAOYSA-N |
Chemical properties
| Hydrogen bond acceptors | 8 |
| Hydrogen bond donors | 2 |
| Rotatable bonds | 7 |
| Molecular weight (Da) | 604.2 |
Drug properties
| Molecular type | Small molecule |
| Physiological/Surrogate | Surrogate |
| Approved drug | No |
Database connections
Sankey plot
Compound is not listed as a drug.
Bioactivities
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| PAF | PTAFR | Guinea pig | Platelet-activating factor | A | pKi | 8.15 | 8.23 | 8.3 | ChEMBL |
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| PAF | PTAFR | Guinea pig | Platelet-activating factor | A | pIC50 | 8.37 | 8.37 | 8.37 | ChEMBL |
| PAF | PTAFR | Human | Platelet-activating factor | A | pIC50 | 7.5 | 8.1 | 8.7 | ChEMBL |