urocortin 2
SMILES | None |
InChIKey | PIXFIEBACLDPNF-SKCWXFKWSA-N |
Sequence | IVLSLDVPIGLLQILLEQARARAAREQATTNARILARV |
Chemical properties
Hydrogen bond acceptors | None |
Hydrogen bond donors | None |
Rotatable bonds | None |
Molecular weight (Da) |
Drug properties
Molecular type | Peptide |
Physiological/Surrogate | Endogenous |
Approved drug | No |
Database connections
Sankey plot
Compound is not listed as a drug.
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
CRF1 | CRFR1 | Human | Corticotropin-releasing factor | B1 | pKd | 5.3 | 5.35 | 5.4 | Guide to Pharmacology |
CRF2 | CRFR2 | Human | Corticotropin-releasing factor | B1 | pKd | 8.5 | 8.55 | 8.6 | Guide to Pharmacology |
CRF2 | CRFR2 | Mouse | Corticotropin-releasing factor | B1 | pKd | 9.3 | 9.3 | 9.3 | Guide to Pharmacology |
CRF2 | CRFR2 | Rat | Corticotropin-releasing factor | B1 | pKd | 8.8 | 8.8 | 8.8 | Guide to Pharmacology |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
CRF2 | CRFR2 | Mouse | Corticotropin-releasing factor | B1 | pEC50 | 8.37 | 8.37 | 8.37 | ChEMBL |