UR-PG146


SMILES O=C(NC(=NCCCc1cnc[nH]1)N)CSCc1nc[nH]c1C
InChIKey ZOBGKPFWPWGQOI-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 4
Rotatable bonds 8
Molecular weight (Da) 335.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H1 HRH1 Human Histamine A pKi 4.4 4.4 4.4 Guide to Pharmacology
H2 HRH2 Human Histamine A pKi 6.0 6.0 6.0 Guide to Pharmacology
H1 HRH1 Guinea pig Histamine A pKd 5.37 5.37 5.37 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database