valsartan


SMILES CCCCC(=O)N([C@H](C(=O)O)C(C)C)Cc1ccc(cc1)c1ccccc1c1nnn[nH]1
InChIKey ACWBQPMHZXGDFX-QFIPXVFZSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 10
Molecular weight (Da) 435.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug Yes

Database connections

Sankey plot

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
AT1 AGTR1 Human Angiotensin A pKi 5.33 6.92 8.52 ChEMBL
AT1 AGTR1 Human Angiotensin A pKi 8.27 8.27 8.27 Drug Central
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
AT1 AGTR1 Human Angiotensin A pIC50 8.8 8.75 9.0 Guide to Pharmacology
BLT2 LT4R2 Human Leukotriene A pEC50 4.8 4.8 4.8 ChEMBL
AT1 AGTRA Rat Angiotensin A pIC50 8.47 8.47 8.47 ChEMBL
AT1 AGTRB Rat Angiotensin A pIC50 8.72 8.72 8.72 ChEMBL
AT1 AGTR1 Human Angiotensin A pIC50 8.13 8.35 8.57 ChEMBL
AT1 AGTRB Rat Angiotensin A pIC50 8.06 8.06 8.06 Drug Central
AT1 AGTRA Rat Angiotensin A pIC50 8.07 8.07 8.07 Drug Central